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Clinical Research

This randomized controlled trial tested a topical exosome-containing formulation blended with botanical extracts in men with androgenetic alopecia.

Key findings:

  • Demonstrated improvements in scalp coverage and hair density compared to placebo.
  • Randomized design adds strength despite the small sample size.
  • Authors noted results were encouraging and warranted larger, longer trials.


👉 Read the full study (Amini et al., 2025, Life)

This prospective study (30 male participants, ages 22–65, Norwood–Hamilton III–VI) evaluated the effect of injecting exosomes into the scalp of patients with androgenetic alopecia.

Key findings:

  • Hair density increased significantly from approximately 149.7 hairs/cm² (pre-treatment) to 153.6 hairs/cm² at 4 weeks, and further to 157 hairs/cm² at 12 weeks (both with p < 0.05)  .
  • Patient satisfaction scores also rose significantly between weeks 4 and 12  .
  • No side effects or complications were reported, indicating a favorable safety profile

Read the full study (Ersan et al., 2024, Aesthetic Plastic Surgery)

This retrospective analysis of 39 patients with androgenetic alopecia investigated the outcomes of exosome therapy.

Key findings:

  • Patients experienced improvements in both hair density and thickness following exosome treatment.
  • The study highlights exosomes as a promising regenerative option for androgenetic alopecia.
  • Though non-randomized, the series adds valuable real-world clinical data.


👉 Read the full study (Park et al., 2022, Journal of Cosmetic Dermatology)

This systematic review (Queen et al., 2025; Dermatologic Surgery) analyzed clinical studies, case reports, case series, and trials on exosome treatments for hair loss.

Key findings:

  • Identified nine clinical studies involving a total of 125 patients treated with exosomes for alopecia.
  • Side effects were rare among those treated, suggesting a promising safety profile.
  • Authors emphasized the need for larger, well-designed trials with longer follow-up and consistent manufacturing standards to better assess efficacy and safety.


👉 Read the full review (Queen et al., 2025, Dermatologic Surgery)